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Many states have legalized cannabis (marijuana) for medical use and for recreational purposes. It has been promoted as a replacement for opioids in the treatment of pain and even as a substitute for opioids in the treatment of addiction. This course will explore the rationale for the use of opioid and non-opioid analgesics in the management of acute dental pain. This course will also explore the various dosage forms of cannabis, its routes of administration, adverse effects, effects on dental treatment, and its potential use in managing pain and addiction.